How Do Birth Control Pills Work?
- Duly Care
- Jun 23
- 7 min read
Birth control pills are one of the most popular and effective methods of preventing pregnancy, but how do they actually work? Whether you opt for Combined Oral Contraceptives Pills (COCPs) or Progestin-Only Pills (POPs), understanding how these pills work can help you use them more effectively and confidently.
Birth control pills are not just about preventing pregnancy - they’re about giving individuals control over their reproductive health and future. If you’re considering starting the birth control pill or simply curious about how it works, this blog will break down the science behind these tiny but powerful pills.
Key Takeaways:
Hormones Are the Key Players: Birth control pills use synthetic hormones (estrogen and progestin) to mimic and alter the natural hormonal cycle, which is essential for regulating ovulation and pregnancy.
Two Types of Pills: There are two main types of birth control pills - Combined Oral Contraceptive Pills (COCPs), which contain both estrogen and progestin, and Progestin-Only Pills (POPs), which contain only progestin. Each type works differently but is highly effective when used correctly.
How COCPs Work: COCPs prevent pregnancy by stopping ovulation, thickening the cervical mucus to block sperm, and thinning the uterine lining to prevent implantation of a fertilized egg.
How POPs Work: POPs primarily prevent pregnancy by thickening cervical mucus and some POPs may suppress ovulation. They are a great option for those who cannot take estrogen.
The Role of Hormones in the Menstrual Cycle

Hormones are chemical messengers produced by the body's endocrine glands that play a crucial role in regulating various physiological processes, including growth, metabolism, and reproduction. They work by carrying signals through the bloodstream to specific organs and tissues, influencing how cells and organs function.
Hormones Involved in the Menstrual Cycle
Estrogen: This hormone is produced by the ovaries and plays a crucial role in developing and maintaining the female reproductive system.
Progesterone: After ovulation, the corpus luteum (the remnant of the follicle that released the egg) secretes progesterone. This hormone prepares the uterus for a potential pregnancy by maintaining the uterine lining.
Gonadotropin-Releasing Hormone (GnRH): Produced by the hypothalamus, GnRH is the "master regulator" of the menstrual cycle. It signals the pituitary gland to release Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH), which are essential for ovulation and hormone production.
Follicle-Stimulating Hormone (FSH): Secreted by the pituitary gland, FSH stimulates the growth of ovarian follicles, each containing an egg.
Luteinizing Hormone (LH): Also released by the pituitary gland, a surge in LH is related to the release of an egg from the ovary.
Phases of the Menstrual Cycle
The menstrual cycle is divided into four main phases:
Menstrual Phase (Days 1-5): The cycle begins with menstruation, where the uterine lining sheds due to low levels of estrogen and progesterone. This phase occurs because the body did not become pregnant during the previous cycle, so it sheds the uterine lining in preparation for a new cycle.
Follicular Phase (Days 1-13): FSH stimulates the growth of ovarian follicles. As these follicles develop, they produce estrogen, which thickens the uterine lining. This phase prepares the uterus for a potential pregnancy by thickening its lining and developing an egg for ovulation.
Ovulation (Day 14): A surge in LH causes the dominant follicle to release an egg. This egg travels down the fallopian tube, where it may be fertilized by sperm. Ovulation is the body's way of releasing an egg for potential fertilization and pregnancy.
Luteal Phase (Days 15-28): After ovulation, the corpus luteum produces progesterone to maintain the uterine lining. If fertilization does not occur, progesterone levels drop, leading to the next menstrual period. This phase supports the implantation of a fertilized egg into the uterine lining. If no fertilization occurs, the cycle restarts with menstruation.
How do Birth Control Pills Work?

Birth control pills are one of the most widely used methods of preventing pregnancy. They work by regulating the body’s natural hormonal cycle. There are two main types of birth control pills: Combined Oral Contraceptive Pills (COCPs) and Progestin-Only Pills (POPs): each type works slightly differently, but both are highly effective when used correctly.
Types of Birth Control Pills
Combined Oral Contraceptives (COCPs): These pills contain synthetic versions of the two hormones: estrogen and progesterone (specifically, a synthetic form called progestin). COCPs are the most commonly prescribed type of birth control pill.
Progestin-Only Pills (POPs): Also known as the "mini-pill," these pills contain only progestin (no estrogen). They are often recommended for women who cannot take estrogen due to health concerns, such as a history of blood clots, high blood pressure, or breastfeeding.
How Combined Oral Contraceptive Pills (COCPs) Work
Preventing Ovulation
The synthetic estrogen and progestin in COCPs mimic the natural hormones in the body. They trick the brain into thinking that ovulation has already occurred, which suppresses the release of Gonadotropin-Releasing Hormone (GnRH) from the hypothalamus. Without GnRH, the pituitary gland does not release Follicle-Stimulating Hormone (FSH) or Luteinizing Hormone (LH), both of which are essential for ovulation.
FSH normally stimulates the growth of follicles in the ovaries, which contain eggs. Without FSH, follicles do not mature, and no egg is released. LH triggers the release of a mature egg from the ovary (ovulation). By suppressing LH, COCPs ensure that ovulation does not occur.
Additional Note: The suppression of ovulation is the most effective mechanism of COCPs. If ovulation is prevented, the other mechanisms (thickening cervical mucus and thinning the uterine lining) serve as secondary safeguards.
Thickening Cervical Mucus
During a natural menstrual cycle, cervical mucus becomes thin, clear, and stretchy around ovulation to facilitate sperm movement. Progestin in COCPs alters the mucus, making it thicker, cloudier, and less permeable.
The thickened mucus acts like a physical barrier, trapping sperm and preventing them from traveling through the cervix into the uterus and fallopian tubes. This is particularly effective because sperm rely on the slippery, watery mucus to swim effectively.
Additional Note: This mechanism is especially important in cases where ovulation is not fully suppressed (e.g., if a pill is missed or taken late).
Thinning the Uterine Lining
The uterine lining (endometrium) thickens during the menstrual cycle to prepare for the potential implantation of a fertilised egg. The synthetic hormones in COCPs reduce the growth of the endometrium, making it thinner and less nutrient-rich.
Even if ovulation occurs and an egg is fertilised, the thin uterine lining makes it difficult for the fertilised egg to attach and grow. This is a backup mechanism to prevent pregnancy.
Additional Note: This mechanism is sometimes misunderstood as causing an "abortion," but it is not the same. Birth control pills primarily prevent fertilisation, and thinning the uterine lining is a secondary effect.
How Progestin-Only Pills (POPs) Work

Thickening Cervical Mucus
Like COCPs, POPs rely heavily on thickening cervical mucus to block sperm. This is the most consistent and reliable way POPs prevent pregnancy.
Because POPs do not contain estrogen, their effectiveness depends heavily on consistent use. Even a delay of a few hours in taking the pill can reduce its ability to thicken cervical mucus, increasing the risk of pregnancy.
Sometimes Preventing Ovulation
POPs do not always suppress ovulation because they lack estrogen, which is more effective at inhibiting FSH and LH. In some women, POPs may suppress ovulation, but this varies depending on individual hormone levels and how consistently the pill is taken.
When POPs do suppress ovulation, it is usually by inhibiting the LH surge, which is necessary for the release of an egg.
Additional Note: Because ovulation suppression is not guaranteed with POPs, they are considered slightly less effective than COCPs for preventing pregnancy.
Changing the Uterine Lining
Similar to COCPs, POPs can thin the uterine lining, making it less receptive to implantation. However, this effect is less pronounced than with COCPs because POPs contain only progestin.
This is a secondary mechanism and is not the primary way POPs prevent pregnancy.
Conclusion
Birth control pills are a reliable and effective method of contraception, offering not only pregnancy prevention but also the added benefit of regulating menstrual cycles and managing various health conditions.
For anyone considering birth control pills, it’s essential to consult a doctor to find the best option tailored to your needs. Stay informed about your contraceptive choices to make empowered and informed decisions about your health.
Frequently Asked Questions (FAQs)
How soon do birth control pills start working?
Birth control pills generally start working within 7 days if taken correctly. However, it's best to use additional protection (like condoms) during the first 7 days to ensure effectiveness.
Can birth control pills help with acne?
Yes, certain birth control pills can reduce androgen levels, which are associated with acne. This is why they are often prescribed to manage hormonal acne.
Can birth control pills cause weight gain?
Birth control pills may cause minor fluid retention and changes in appetite, but they don't directly cause significant weight gain. Any weight changes are typically temporary.
What happens if I miss a birth control pill?
If you miss one pill, take it as soon as you remember. If you miss two or more pills, follow the instructions on the pill package or consult your doctor. Using a backup method like condoms is recommended if you miss multiple pills.
Important
This blog, including its text, images, and infographics, is for educational purposes only and not a substitute for professional medical advice. For personalized advice, always consult a doctor.
Further Reading
For more details on this or related topics, refer to the papers listed in references below, or check out the other blogs on our website dulycare.in.
References
UK National Health Service. Combined Contraceptive Pill. 2023. https://www.nhs.uk/conditions/contraception/combined-contraceptive-pill
The Faculty of Sexual and Reproductive Healthcare. Combined Hormonal Contraception. 2023. https://www.fsrh.org/standards-and-guidance/documents/combined-hormonal-contraception/
Patient. Combined Oral Contraceptive Pill: First Prescription. 2023. https://patient.info/doctor/combined-oral-contraceptive-pill-first-prescription#ref-4
International Journal of Endocrinology & Metabolism. Non-Contraceptive Benefits of Oral Hormonal Contraceptives. 2013. https://ijem.sums.ac.ir/article_4158.html
American College of Obstetricians and Gynecologists (ACOG). Birth Control. Accessed on 7 February 2025. https://www.acog.org/womens-health/faqs/birth-control
World Health Organization (WHO). Family Planning: A Global Handbook for Providers. 2022. https://www.who.int/publications/i/item/9780999203705
Science Direct. Yen & Jaffe's Reproductive Endocrinology 8th edition. 2019. https://www.sciencedirect.com/book/9780323479127/yen-and-jaffes-reproductive-endocrinology
World Health Orgnaisation (WHO). Medical eligibility criteria for contraceptive use. 2015. https://iris.who.int/bitstream/handle/10665/181468/9789241549158_eng.pdf
The Cochrane Database of Systematic Reviews. Oral contraceptive pill for primary dysmenorrhoea. 2009. https://pubmed.ncbi.nlm.nih.gov/19821293/
Journal of Clinical Medicine. Bleeding Patterns of Oral Contraceptives with a Cyclic Dosing Regimen: An Overview. 2022. https://pmc.ncbi.nlm.nih.gov/articles/PMC9369460/
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